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Marek's Disease

Synonyms: 
early mortality syndrome
transient paralysis
skin leukosis
leukosis
lymphomatosis
rnage paralysis
neurolymphomatosis gallinarium
neuritis
polyneuritis
Marek's disease virus
cytolytic infection
atherosclerosis
persistent neurological disease
Is Latin Name: 
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Marek's Disease

Marek's Disease

Etiology

Marek's disease (MD) is a transmissible neoplastic disease, primarily affecting chickens. The disease is caused by a cell-associated herpesvirus, containing double-stranded DNA. There are three serotypes of MDV but oncogenicity is only associated with serotype 1 MDVs. Within this serotype however, there are many strains of MDV, whose pathogenicity varies widely. Subsequently, clinical signs in infected chickens vary from asymptomatic infection to neurologic disease, skin disease, and ocular lesions.

Host Range

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